Table 2.

Significantly Enriched Pathways after Next Neighbor Expansion

	49 Primary candidates + secondary candidates from next neighbor expansion
Pathway	Total no.⁎	Expected no.†	Observed no.‡	P value§
Apoptosis signaling pathway	131	0.53	15	1.78E-15
Toll-like receptor signaling pathway	71	0.29	10	7.50E-11
Inflammation mediated by chemokine and cytokine signaling pathway	315	1.28	7	4.40E-02

^⁎Total number of genes in the given pathway in the PANTHER database.

^†Expected number (resulting from sample size) of candidates in any random dataset.

^‡Observed number (after next neighbor expansion) of candidates.

^§Bonferroni corrected P value for overrepresentation of the given pathway.