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Target-controlled infusion to reach pseudosteady state of [11C]CITin cerebellum. As expected, there was high uptake localized to striatum, as shown in a trans-axial projection of a representative subject (A). The pseudosteady state of [11C]CITin cerebellum resulted in elevated, close to irreversible striatal uptake (B). Error bars indicate SEM (n = 5).
