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Kinetic parameters for [11C]CIT PK/PD in striatum determined from the simplified reference tissue model. The majority of variation in BP and DVR is due to the elevated values in subject 3.
| Parameter | Subject 1 | Subject 2 | Subject 3 | Subject 4 | Subject 5 | Average | SEM |
|---|---|---|---|---|---|---|---|
| R1 | 0.58 | 1.09 | 1.47 | 1.17 | 0.84 | 1.03 | 0.15 |
| k2 | 0.13 | 0.08 | 0.12 | 0.07 | 0.07 | 0.10 | 0.01 |
| BP | 3.85 | 4.18 | 8.14 | 4.69 | 5.87 | 5.34 | 0.78 |
| DVR | 4.85 | 5.18 | 9.14 | 5.69 | 6.87 | 6.34 | 0.78 |
| DVR ref | 1 | 1 | 1 | 1 | 1 | 1 | - |
