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Occupancy model parameters describing the initial pharmacodynamics of bupropion and GBR-12909. Best fit was obtained by minimizing the residual sum of squares (RSS).
| Parameter | Unit | Bupropion | GBR-12909 |
|---|---|---|---|
| Occ0 | % | 84.5 | 76.1 |
| koff | min-1 | 0.021 | 0.0 |
| Model fit (RSS) | 0.33 | 1.68 |
