. 2011 Mar 15;104(8):1262–1269. doi: 10.1038/bjc.2011.85

Table 2. Modulation of investigated markers by treatment.

	Baseline		Day 15			Day 57			Day 155			PD
	Mean (pg ml⁻¹)	Median (pg ml⁻¹)	Mean (pg ml⁻¹)	Median (pg ml⁻¹)	% of baseline median values	Mean (pg ml⁻¹)	Median (pg ml⁻¹)	% of baseline median values	Mean (pg ml⁻¹)	Median (pg ml⁻¹)	% of baseline median values	Mean (pg ml⁻¹)	Median (pg ml⁻¹)	% of baseline median values
VEGF	86.32	57.68	49.23	39.96	61.47*	42.73	39.49	60.53**	39.38	36.66	38.80**	37.47	37.21	54.30***
PlGF	33.87	34.87	—	—	—	53.72	52.56	179.88***	45.36	46.89	142.82*	39.32	40.19	119.2
sVEGFR-2	4179.05	4163.60	—	—	—	4247.80	4244.00	100.81	4514.40	4234.10	99.41	6641.60	4708.40	107.91
TSP-1	451.52	461.31	—	—	—	432.55	483.94	98.13	380.87	391.74	86.15	568.21	479.55	167.79

Abbreviations: PlGF=placental growth factor; sVEGFR-2=soluble vascular endothelial growth factor receptor 2; VEGF=vascular endothelial growth factor; TSP-1=thrombospondin-1.

P<0.1; *P<0.05; **P<0.01; ***P<0.001 compared with baseline level.