Table 1. Number of BRCA1 and BRCA2 mutation carriers by study.

Study	Country of residence	BRCA1	BRCA2	Genotyping platform
Spanish National Cancer Centrea,b	Spain and Greecea	144	147	Taqman
Catalan Institute of Oncologyb	Spain	144	177	Taqman
Hereditary Breast and Ovarian study Netherlands	The Netherlands	791	308	iPlex
Epidemiological study of BRCA1 and BRCA2 mutation carriers	UK and Eire	997	817	iPlex
Fox Chase Cancer Center	USA	83	54	iPlex
Georgetown	USA	43	35	iPlex
Helsinki Breast Cancer Study	Finland	103	104	iPlex
Iceland Landspitali – University Hospital	Iceland	0	133	iPlex
Kathleen Cuningham Consortium for Research into Familial Breast Cancer	Australia	592	478	iPlex
Mayo Clinic	USA	231	126	iPlex
Milan Breast Cancer Study Groupb	Italy	413	252	Taqman
Pisa Breast Cancer Study	Italy	86	56	iPlex
Swedish Breast Cancer Study	Sweden	536	176	iPlex
University of Pennsylvania	USA	317	153	iPlex
Totalc		4480	3016

^aThe Spanish National Cancer Centre series consisted of mutation carriers from the Spanish Consortium for the Study of Genetic Modifiers of BRCA1 and BRCA2 and the National Centre for Sensor Research Demokritos, Athens and Greece.

^bSeries included in stage I of the study.

^cMutation carriers that failed genotyping are not included in the totals.