Table 3. Relation of neuroticism measures to baseline level of global cognition and rate of global cognitive decline ^*.

Model Terms	Estimate	Standard Error	t	df	P
Anxiety	-0.009	0.003	-2.87	780	.004
Anxiety × time	-0.003	0.001	-2.59	2,680	.010
Angry hostility	-0.006	0.004	-1.63	780	.103
Angry hostility × time	-0.001	0.001	-0.89	2,680	.373
Depression	-0.015	0.003	-4.41	780	<.001
Depression × time	-0.002	0.001	-1.95	2,680	.052
Self-consciousness	-0.010	0.004	-2.60	780	.010
Self-consciousness × time	-0.001	0.001	-1.15	2,680	.250
Impulsiveness	-0.002	0.004	-0.67	780	.503
Impulsiveness × time	-0.001	0.001	-1.21	2,680	.228
Vulnerability	-0.014	0.004	-3.53	780	<.001
Vulnerability × time	-0.004	0.001	-2.76	2,680	.006

^*From separate mixed-effects regression models adjusted for age, sex, and education. Results show the effect of a 1-unit change in trait score on the cognitive outcomes.