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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Am J Geriatr Psychiatry. 2011 Apr;19(4):327–334. doi: 10.1097/JGP.0b013e31820119da

Table 4. Relation of neuroticism measures to annual rate of change in specific cognitive functions*.

Neuroticism Facet Episodic memory Estimate (SE) p Semantic memory Estimate (SE) p Working memory Estimate (SE) p Perceptual speed Estimate (SE) p Visuospatial Ability Estimate (SE) p
Anxiety -0.002 (0.001) .119 -0.001 (0.001) .590 -0.004 (0.001) <.001 -0.005 (0.001) <.001 -0.000 (0.002) .853
Angry hostility -0.001 (0.001) .436 -0.000 (0.001) .947 -0.002 (0.002) .271 -0.003 (0.001) .047 -0.001 (0.002) .703
Depression -0.003 (0.001) .045 -0.000 (0.001) .751 -0.003 (0.001) .059 -0.003 (0.001) .019 0.001 (0.002) .353
Self-consciousness -0.002 (0.002) .230 0.001 (0.001) .733 -0.003 (0.002) .060 -0.002 (0.002) .195 0.001 (0.002) .638
Impulsiveness -0.002 (0.001) .237 -0.001 (0.001) .571 -0.003 (0.002) .035 -0.003 (0.001) .020 -0.001 (0.002) .570
Vulnerability -0.004 (0.002) .029 -0.002 (0.002) .284 -0.005 (0.002) .006 -0.005 (0.002) .004 -0.001 (0.002) .763
*

Estimates of the relation of each facet to change in each cognitive outcome from separate mixed-effects regression models adjusted for age, sex, and education. Results show the effect of a 1-unit change in trait score on annual rate of cognitive change. P-values are based on the t-distribution with degrees of freedom equal to 2,623 for analyses of episodic memory, 2,600 for semantic memory, 2,679 for working memory, 2,573 for perceptual speed, and 2,557 for visuospatial ability.