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. 2010 Dec 1;30(48):16304–16313. doi: 10.1523/JNEUROSCI.4333-10.2010

Figure 4.

Figure 4.

TBS enhances acuity and contrast sensitivity. A, LTP was induced as described previously (Fig. 3). The following day, awake, head-fixed mice were exposed to stimuli across a range of spatial frequencies (0.05, 0.15. 0.3, 0.45, 0.6, 0.8, 1.0 cycle/°) at a set oblique orientation. VEP amplitude was greater across all spatial frequencies in the TBS hemisphere (black circles) than the control hemisphere (white circles; n = 11). Example VEP waveforms are presented from both hemispheres above the relevant graph points. Calibration: 100 μV, 50 ms. B, TBS-induced gains in spatial acuity are revealed by normalizing VEPs in the TBS hemisphere (black circles) to the control hemisphere. C, VEP amplitude was also greater in the TBS hemisphere than the control hemisphere across a range of contrasts (0, 1.5, 3.125, 6.25, 12.5, 25, 50, and 100%). Example waveforms are presented at the top of the panel. D, TBS-induced gains in contrast sensitivity are revealed by normalizing VEPs in the TBS hemisphere to those in the control hemisphere. Error bars in all graphs are SEM.