Figure 3. TLR3 dependence of activation of splenic and bone marrow derived DC.
CD86 expression of WT, MDA5−/− and TLR3−/− splenic DC, FL-DC and GM-DC after 24 h treatment with dsRNA (540 bp), pIC or medium alone (Ctrl). Data shown are mean +SEM of triplicate DC cultures and are representative of four independent experiments.