FIGURE 2.

Micro-CT imaging of vascular casts obtained from a swine model of atherosclerotic renal artery stenosis. Atherosclerosis produced by cholesterol feeding induces small vessel proliferation and disturbed endothelial function (middle panel). The kidney beyond a main renal arterial occlusive lesion induced by copper stent experiences dropout (“rarefication”) of small vessels within both cortex and medulla and accelerated tissue fibrosis. From Lerman and Chade, with permission ⁹⁰.