Table 3.

Systemic Disorders with Proven Involvement of NFAT5 Target Genes

Condition/Disorder	Target gene	Refs.
Diabetic microvascular lesions	Aldose reductase Inflammatory cytokines?	[55]
Adaptive immunity	Genes involved in osmoadaptation Immune modulatory cytokines B cell activating factor (BAFF)	[14, 23, 42]
Salt-sensitive hypertension	VEGF-C	[24, 56]