Table 3.
Baseline and follow-up scores and clinical characteristics of study participants by subgroup over the 2-year interval. Means (± SE)
| Baseline scores | Follow-up scores | |||||||
|---|---|---|---|---|---|---|---|---|
| Amnestic MCI | Nonamnestic MCI | Amnestic MCI | Nonamnestic MCI | |||||
| Single Domain |
Multiple Domain |
Single Domain |
Multiple Domain |
Single Domain |
Multiple Domain |
Single Domain |
Multiple Domain |
|
| Logical Memory WMS-R |
4.78 (0.51) |
2.71 (0.46) |
10.82 (0.57) |
9.92 (0.74) |
5.52 (0.72) |
2.91 (0.64) |
8.55 (0.80) |
6.15 (1.04) |
| Boston Naming Test |
28.04 (0.76) |
24.11 (0.67) |
26.48 (0.84) |
23.69 (1.12) |
27.14 (0.87) |
22.78 (0.77) |
25.87 (0.96) |
22.77 (1.28) |
| Phonemic Fluency |
40.59 (2.19) |
36.41 (1.95) |
35.35 (2.37) |
33.00 (3.15) |
38.56 (2.25) |
31.22 (2.01) |
31.26 (2.44) |
29.92 (3.24) |
| Category Fluency | 22.73 (1.30) |
22.31 (1.12) |
27.44 (1.38) |
23.77 (1.84) |
24.81 (1.51) |
18.17 (1.30) |
26.09 (1.60) |
20.31 (2.13) |
| Clock Drawing Test |
9.57 (0.25) |
7.77 (0.22) |
8.57 (0.27) |
7.46 (0.36) |
9.00 (0.36) |
6.82 (0.32) |
8.13 (0.39) |
7.15 (0.52) |
| Alternate Uses Test |
13.18 (0.95) |
7.67 (0.88) |
12.04 (1.05) |
7.75 (1.45) |
12.75 (1.02) |
6.15 (0.94) |
10.74 (1.13) |
6.83 (1.56) |
| Random Number Generation |
0.68 (0.04) |
0.63 (0.04) |
0.67 (0.04) |
0.70 (0.06) |
0.63 (0.04) |
0.70 (0.04) |
0.63 (0.05) |
0.85 (0.07) |
| Tinker Toy Test | 8.43 (0.38) |
7.75 (0.35) |
8.65 (0.42) |
6.58 (0.58) |
8.36 (0.41) |
7.22 (0.39) |
7.74 (0.46) |
6.92 (0.63) |
| D-KEFS Stroop Test |
10.19 (0.68) |
9.35 (0.61) |
9.39 (0.74) |
8.92 (1.02) |
8.44 (0.84) |
6.59 (0.75) |
9.65 (0.91) |
8.67 (1.26) |
| Hayling Test | 4.75 (0.30) |
3.84 (0.28) |
4.26 (0.33) |
3.92 (0.45) |
3.68 (0.31) |
2.63 (0.29) |
3.39 (0.34) |
3.58 (0.48) |
| Completions & Corrections Test |
9.85 (0.39) |
9.23 (0.37) |
9.68 (0.43) |
9.45 (0.61) |
8.11 (0.54) |
7.84 (0.50) |
9.18 (0.59) |
8.82 (0.84) |
| Porteus Maze Test |
14.98 (0.49) |
13.69 (0.46) |
14.08 (0.54) |
10.67 (0.75) |
14.13 (0.59) |
12.30 (0.55) |
13.43 (0.65) |
9.71 (0.89) |
| D-KEFS Tower Test |
9.79 (0.52) |
9.25 (0.49) |
9.43 (0.58) |
8.25 (0.80) |
10.75 (0.65) |
9.59 (0.61) |
10.00 (0.72) |
7.42 (1.00) |
| Tic-Tac-Toe | −4.71 (0.42) |
−4.45 (0.40) |
−5.04 (0.46) |
−5.55 (0.67) |
−5.14 (0.43) |
−5.35 (0.41) |
−5.00 (0.48) |
−6.18 (0.69) |
| D-KEFS Sorting Test |
11.86 (0.54) |
11.22 (0.51) |
11.04 (0.60) |
10.25 (0.83) |
12.89 (0.45) |
11.37 (0.42) |
12.74 (0.49) |
10.67 (0.68) |
| Brixton Spatial Anticipation Test |
4.68 (0.41) |
4.22 (0.38) |
4.61 (0.45) |
3.00 (0.62) |
4.64 (0.38) |
3.97 (0.35) |
3.96 (0.42) |
3.08 (0.58) |
| Verbal Concept Attainment Test |
16.89 (0.70) |
15.03 (0.66) |
16.57 (0.77) |
15.83 (1.07) |
15.75 (0.87) |
13.28 (0.82) |
16.09 (0.96) |
13.83 (1.33) |
| Stanford Binet Absurdities Test |
29.29 (0.59) |
26.58 (0.54) |
27.70 (0.65) |
24.33 (0.90) |
28.39 (0.73) |
25.06 (0.68) |
26.43 (0.81) |
23.67 (1.12) |
| Iowa Gambling Test |
4.37 (1.26) |
3.10 (1.19) |
2.74 (1.36) |
2.20 (2.06) |
2.04 (1.01) |
1.60 (0.95) |
0.70 (1.09) |
3.40 (1.65) |
| Experimental Judgment Test |
9.74 (0.97) |
9.75 (0.89) |
7.16 (1.05) |
6.47 (1.46) |
10.16 (1.52) |
13.47 (1.40) |
7.33 (1.65) |
11.03 (2.28) |
| Trail Making Test | 69.43 (9.44) |
66.68 (8.97) |
87.48 (10.42) |
90.42 (14.42) |
70.11 (14.57) |
93.29 (13.85) |
110.74 (16.07) |
118.08 (22.25) |
| Brief Test of Attention |
14.46 (0.69) |
12.19 (0.65) |
13.39 (0.77) |
10.83 (1.06) |
13.07 (0.97) |
10.38 (0.91) |
12.78 (1.07) |
9.83 (1.49) |
| TEA Telephone Search While Counting |
1.45 (0.56) |
3.57 (0.53) |
1.58 (0.61) |
2.77 (0.88) |
2.98 (1.97) |
8.89 (1.84) |
2.07 (2.14) |
4.03 (3.09) |
| Geriatric Depression Scale |
2.33 (0.44) |
2.86 (0.39) |
1.91 (0.49) |
2.54 (0.64) |
3.04 (0.51) |
2.77 (0.45) |
2.00 (0.56) |
2.85 (0.73) |
| ADCS ADL-PI | 3.00 (0.79) |
4.41 (0.70) |
2.63 (0.99) |
6.70 (1.25) |
3.29 (0.88) |
5.97 (0.77) |
3.19 (1.09) |
7.00 (1.38) |
| IQCODE | 3.24 (0.07) |
3.49 (0.06) |
3.35 (0.09) |
3.62 (0.12) |
3.33 (0.09) |
3.79 (0.08) |
3.29 (0.11) |
3.61 (0.15) |
| DEX | 13.44 (2.23) |
15.84 (2.00) |
17.19 (2.78) |
26.60 (3.52) |
13.44 (2.64) |
22.19 (2.37) |
15.19 (3.30) |
25.70 (4.18) |