Table 1.
Gene expression differences tested by microarray and real-time PCR in bear heart and liver
Gene Symbol | Gene Name | RT-PCR | Microarray | ||
---|---|---|---|---|---|
P | log2FC | P | log2FC | ||
HEART | |||||
Acadvl | Acyl-Coenzyme A dehydrogenase, very long chain | 0.034 | 0.122 | <0.001 | 0.747 |
Dnajc8 | DnaJ (Hsp40) homolog, subfamily C, member 8 | 0.008 | 0.270 | <0.001 | 0.698 |
Gapdh | Glyceraldehyde-3-phosphate dehydrogenase | 0.140 | n/a | 0.008 | 0.620 |
Mbip | MAP3K12 binding inhibitory protein 1 | 0.580 | n/a | 0.001 | 0.884 |
Rbm3 | RNA binding motif protein 3 | <0.001 | 2.349 | <0.001 | 2.863 |
Rpl35a | Ribosomal protein L35a | 0.009 | 0.550 | <0.001 | 1.857 |
Rpl7 | Ribosomal protein L7 | 0.004 | 0.533 | <0.001 | 1.243 |
Rps27 | Ribosomal protein S27 | 0.009 | 0.600 | 0.001 | 0.720 |
Adk | Adenosine kinase | 0.015 | -0.164 | 0.006 | -0.534 |
Aldh6a1 | Aldehyde dehydrogenase 6 family, member A1 | <0.001 | -0.974 | 0.001 | -0.893 |
Ank1 | Ankyrin 1, erythrocytic | <0.001 | -1.234 | <0.001 | -1.440 |
Gstz1 | Glutathione transferase zeta 1 | 0.031 | -0.343 | 0.001 | -0.605 |
Ube2v1 | Ubiquitin-conjugating enzyme E2 variant 1 | 0.001 | -0.327 | 0.004 | -0.600 |
LIVER | |||||
Gpc3 | Glypican 3 | <0.001 | 2.307 | <0.001 | 1.965 |
Rplp2 | 60S acidic ribosomal protein P2 | <0.001 | 1.378 | 0.003 | 1.627 |
Cmtm8 | CKLF-like MARVEL transmembrane domain-containing protein 8 | 0.170 | n/a | <0.001 | 1.525 |
Pc | Pyruvate carboxylase | 0.130 | n/a | 0.002 | 1.390 |
Crip2 | Cysteine-rich protein 2 | <0.001 | 1.064 | 0.001 | 1.285 |
A2m | Alpha 2 macroglobulin | 0.003 | 1.287 | 0.004 | 1.249 |
Rpl36 | 60S ribosomal protein L36 | 0.002 | 0.963 | 0.004 | 1.223 |
Brp44l | Brain protein 44-like protein | 0.002 | 1.638 | 0.009 | 1.198 |
Naca | Nascent-polypeptide-associated complex alpha polypeptide variant | <0.001 | 0.714 | 0.001 | 1.182 |
Fgfr2 | Fibroblast growth factor receptor 2 precursor | <0.001 | 1.055 | <0.001 | 1.130 |
Tbca | Tubulin cofactor a | 0.001 | 0.579 | 0.001 | 1.122 |
Rps6 | Ribosomal protein S6 | 0.001 | 0.677 | 0.010 | 1.079 |
Comt | Catechol-O-methyltransferase | <0.001 | -0.741 | 0.001 | -1.817 |
Arg1 | Arginase | 0.016 | -1.418 | 0.009 | -2.050 |
Phyh | Phytanoyl-CoA 2-hydroxylase | 0.002 | -1.328 | 0.004 | -2.105 |
Tinag | Tubulointerstitial nephritis antigen | <0.001 | -1.822 | <0.001 | -2.141 |
Ugt3a2 | UDP glycosyltransferase 3 family, polypeptide A2 | <0.001 | -4.034 | <0.001 | -2.949 |
Fmo5 | Flavin-containing monooxygenase 5 | 0.001 | -2.631 | 0.002 | -3.002 |
Pitrm1 | Pitrilysin metalloprotease 1 | 0.027 | -0.421 | 0.001 | -3.360 |
Inconsistent significance levels for some genes are in bold.