Table 2.

Differentially expressed genes shared between liver and heart in hibernating bears

Gene Symbol	Gene Name	P, Liver	log2FC, Liver	P, Heart	log2FC, Heart
Fatty Acid Catabolism (4 genes)
Aarsd1	Alanyl-tRNA synthetase domain containing 1	0.006	0.638	0.006	0.838
Acadm	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial precursor	0.001	0.510	<0.001	1.138
Acadvl	Acyl-Coenzyme A dehydrogenase, very long chain	0.001	0.842	<0.001	0.747
Hadha	Trifunctional enzyme alpha subunit, mitochondrial precursor	0.007	0.586	0.008	0.556
Protein Biosynthesis (13 genes)
Rps18	40S ribosomal protein S18	0.001	0.899	0.002	1.144
Rps29	Ribosomal protein S29	0.006	0.802	0.001	0.843
Rbm3	RNA binding motif protein 3	<0.001	2.681	<0.001	2.863
Rpl18a	60S ribosomal protein L18a	<0.001	0.606	0.002	0.607
Rpl22	Ribosomal protein L22	0.006	1.398	0.004	0.923
Rpl24	Ribosomal protein L24	0.005	0.935	0.003	0.725
Rpl27a	Ribosomal protein L27a-like	0.004	1.349	0.008	0.927
Rpl30	Ribosomal protein L30	0.004	0.862	0.002	1.010
Rpl35a	60S ribosomal protein L35a	0.001	0.937	<0.001	1.857
Rpl7	60S ribosomal protein L7	0.008	0.767	<0.001	1.243
Rplp2	60S acidic ribosomal protein P2	0.003	1.627	0.001	0.732
Rps23	Ribosomal protein S23	<0.001	1.213	0.001	1.793
Rps24	Ribosomal protein S24	0.008	0.802	0.002	1.000
Amino Acid Catabolic Processes (3 genes)
Aldh6a1	Aldehyde dehydrogenase 6 family, member A1	0.006	-1.086	0.001	-0.893
Got1	Aspartate aminotransferase	<0.001	-1.014	0.002	-0.644
Lap3	Leucine aminopeptidase 3 protein	0.008	-0.943	0.001	-0.771
Other GO Categories (13 genes)
Cd2bp2	CD2 (cytoplasmic tail) binding protein 2	0.005	0.981	0.008	0.614
Cdk2	Cyclin-dependent kinase 2	0.001	0.755	0.005	0.827
Cd2bp2	CD2 (cytoplasmic tail) binding protein 2	0.005	0.981	0.008	0.614
Hnrnpa1	Heterogeneous nuclear ribonucleoprotein A1	0.004	1.418	0.006	1.048
St7	Suppression of tumorigenicity 7	0.001	0.909	0.003	0.965
Tinp1	TGF-beta-inducible nuclear protein 1	0.010	0.678	<0.001	0.813
Cyp1a2	Cytochrome P450, family 1, subfamily A, polypeptide 2	0.007	-2.290	0.005	-0.594
Phyh	Phytanoyl-CoA 2-hydroxylase	0.004	-2.105	0.008	-0.865
Gbe1	Glycogen branching enzyme	0.007	-0.641	0.002	0.838
Glrx3	Glutaredoxin-3	0.004	-0.595	0.001	1.011
Kif21a	Kinesin family member 21A	0.010	1.000	0.009	-0.504
Mnat1	Menage a trois homolog 1, cyclin H assembly factor	0.007	-0.675	0.006	1.067
Ppm1k	Protein phosphatase 1K	0.005	1.107	0.007	-0.615