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. 2011 Apr 18;6(4):e18796. doi: 10.1371/journal.pone.0018796

Figure 1. Stromal co-culture increases lateral epithelial cell adhesion.

Figure 1

(A and B). Phase images of 3D BPH-1 acini grown with (B) and without stroma (A) for 8 days, bars  = 50 µm. Thick sections (C,D) and TEM (E,F) of mid-sections through BPH-1 acini, grown with (D,F) and without stroma (C,E). Bar  = 20 (E) or 50 µm (F). (G and H). High magnification TEM images of the junctions marked by the asterisks in (E) and (F). The lateral cell-cell contact shown in (H) is highlighted by white arrows, bars  = 5 µm. Images are representative of three spheroids analysed per experiment. The values in table 1 have standard deviations of ±15%, #  = p<0.018.