Table 1.
Dose escalation
| Cohort | Safingol (mg/m2) |
Cisplatin (mg/m2) |
N |
|---|---|---|---|
| 1 | 60 | 75 | 4 |
| 2 | 120 | 75 | 3 |
| 3 | 240 | 75 | 3 |
| 4 | 240 | 60 | 6 |
| 5 | 360 | 60 | 3 |
| 6 | 480 | 60 | 3 |
| 7 | 600 | 60 | 3 |
| 8 | 750 | 60 | 6 |
| 9 | 930 | 60 | 6 |
| 10 | 840 | 60 | 6 |
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