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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Adv Enzyme Regul. 2010 Oct 28;51(1):219–228. doi: 10.1016/j.advenzreg.2010.10.003

Figure 2.

Figure 2

Proposed points of p53-dependent regulation of the sphingolipid pathway after cell stress. DDR: DNA Damage Response, ARF: Alternate Reading Frame product, ATM: Ataxia Telangiectasia Mutated protein, ATR: Ataxia Telangiectasia and Rad3-related protein, p53: Tumor Suppressor Protein p53, SMase: Sphingomyelinase, SK1: Sphingosine Kinase 1, Cer: Ceramide, and S1P: Sphingosine-1-Phosphate.