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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Adv Enzyme Regul. 2010 Oct 28;51(1):51–58. doi: 10.1016/j.advenzreg.2010.09.016

Figure 1. Domain structure of Eukaryotic N-SMase family members.

Figure 1

Shown is a schematic illustration of the known functional domains of ISC1 from S. cerevisiae (Genbank, P40015), human nSMase1 (O60906), human nSMase2 (Q9NY59) and murine MA-nSMase (NP_001182466).