Table 2.

High-Ankle Brachial Index Prevalence and Incidence Ratios for Highest to Lowest Quartile of Anthropometric Measures in the Multi-Ethnic Study of Atherosclerosis (2000-2006)

Anthropometric Measure	Prevalence Ratio for high-ABI (95% CI); n=6208	p-value	Incidence Ratio for high-ABI (95% CI); n=4805	p-value	Incidence Ratio for high-ABI in subjects without diabetes (95% CI); n=4303	p-value
Body Weight (kg): 89.4-158.8 vs. 32.7-66.2	3.7 (2.6-5.2)	<0.001	2.7 (1.9-3.8)	<0.001	2.3 (1.5-3.4)	<0.001
Body Mass Index (kg/m^2): 31-62 vs. 15-25	2.4 (1.8-3.2)	<0.001	2.4 (1.8-3.3)	<0.001	2.1 (1.5-3.1)	0.001
Waist Circumference (cm): 107-167 vs. 59-88	2.3 (1.8-3.1)	<0.001	2.0 (1.4-2.7)	<0.001	1.7 (1.2-2.4)	0.004
Waist to Hip Ratio 0.99-1.30 vs. 0.65-0.87	1.4 (1.0-1.8)	0.01	1.5 (1.1-2.0)	0.03	1.3 (0.9-1.8)	0.30

^*High-Ankle Brachial Index (ABI) is defined as ≥ 1.3

^†Models are fully adjusted for age, gender, ethnic background, smoking status, pack-years smoking, diabetes, systolic blood-pressure, education, IL-6, homocysteine, c-reactive protein, LDL, HDL, urinary albumin creatinine ratio, estimated glomerular filtration rate.

^‡Incidence analysis in those without diabetes is adjusted for the natural log of the Homeostasis Model of Insulin Resistance instead of diabetes

^§All analyses exclude those participants missing baseline ABI measurements or relevant covariates; Incidence analyses additionally exclude those missing follow-up ABI measurements and those with abnormal ABI at baseline (see Methods).

^∥p-values are for linear trend for all quartiles of each measure