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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Cancer Gene Ther. 2011 Jan 14;18(5):326–335. doi: 10.1038/cgt.2010.82

Figure 1. CMI dose response titration of Ad5 [E1-, E2b-]-HER2/neu.

Figure 1

Ad5 naïve BALB/c mice (n=5/group) were immunized three times using a dose of 108, 109 or 1010 VP Ad5 [E1-, E2b-]-HER2/neu or buffer alone (controls). Fourteen days after the final immunization, splenocytes from the mice were assessed by ELISpot analysis. The greatest induction of CMI was achieved using 1010 VP of the vector. For positive controls, splenocytes were exposed to concanavalin A in all ELISpot assays as described (data not shown). The error bars depict the standard error of the mean (SEM).