Fig. 2.

Von Frey test for mechanical hyperalgesia on the contralateral (Contra) and ipsilateral (Ipsi) hindpaws in rats from the sham control (Sham), spinal cord hemisection (Hemi) and hemisection and minocycline treatment (Hemi+Mino) groups. The ipsilateral hindpaw withdrawal threshold was decreased from 2 days after surgery and persisted until postoperative day 28. Administration of minocycline attenuated the decrease of this threshold. ^*p<0.05 vs. sham control group, ^†p<0.05 vs. hemisection group.