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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Neurogastroenterol Motil. 2010 Dec 10;23(3):279–e124. doi: 10.1111/j.1365-2982.2010.01641.x

Figure 4. Apoptosis of DMV neurons induced by PAR agonists.

Figure 4

Apoptosis is induced by PAR1 agonist only. Cultured DMV neurons were treated with agonists specific for PAR1 (SFLLR) ((10−6~10−4M), PAR3 (TFRGAP) (10−4M) or PAR4 (YAPGKF) (10−5 M and 10−4M) for 24 hrs. Apoptosis was analyzed by Tunel (A) and ELISA assay (B). Hu positive cells were counted. Results are expressed as mean±SEM. * p<0.05. Significant difference (P<0.05) was also observed between cells treated with 10−6 M and 10−5 M of SFLLR.