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. Author manuscript; available in PMC: 2011 Apr 19.
Published in final edited form as: Clin Gastroenterol Hepatol. 2009 Jun 10;7(10):1104–1112. doi: 10.1016/j.cgh.2009.05.033

Table 1.

Formulae of noninvasive panels for detection of fibrosis used for the study

Formula Equation

AST to ALT Ratio (AAR) AST/ALT

AST to Platelet Ratio AST/Platelet Count × 100

AST to Platelet Ratio Index (APRI) [(AST/upper limit of normal)/Platelet Count (109/l)] × 100

Cirrhosis Discriminant Score (CDS) Platelet count AST/ALT ratio INR
>340=0 >1.7=0 <1.1=0
280–339=1 1.2–1.7=1 1.1–1.4=1
220–279=2 0.6–1.19=2 >1.4=2
160–219=3 <0.6=3
100–159=4 Score is the sum of
three (0–11)
40–99=5
<40=6

FIB4 Index (Age[years] × AST[U/L])/(platelet [109] X√ALT[U/L])

NAFLD Fibrosis Score −1.675 + (0.037 × Age[years]) + (0.094 × BMI) + (1.13 × IFG/diabetes
[yes=1, no=0]) + (0.99 × AST/ALT) - (0.013 × platelet[109/l]) - (0.66 X
albumin[g/dl])

Goteborg University Cirrhosis Index (GUCI) (AST/ Upper limit of normal ) × INR × 100(Platelet Count)

BARD score Scale 0–4
BMI ≥ 28 kg/m2 = 1 point
AST to ALT Ratio ≥ 0.8 = 2 points
Diabetes mellitus = 1 point
*

ULN for AST: 30 in women, 35 in men