Skip to main content
. Author manuscript; available in PMC: 2011 Apr 19.
Published in final edited form as: Expert Opin Biol Ther. 2009 Mar;9(3):293–306. doi: 10.1517/14712590802715723

Figure 3. Multi-color images of CEST peptides using three different saturation frequencies.

Figure 3

The phantom shown consists of 1 mm tubes inserted into a 5 mm NMR tube, filled with 2.5 mg/ml peptides and buffer as outlined in (A) PBS = phosphate buffered saline; PLR = poly-L-arginine, PLK = poly-L-lysine, PLT = poly-L-threonine. (A) Proton density image. (B) magnetization transfer ratio asymmetry (MTRasym) (± 3.69 p.p.m.) image. (C) MTRasym (± 1.8 p.p.m.) image. (D) MTRasym (± 0.8 p.p.m.) image. (E) Merged image from the three label channels. (F) NH label from the difference between images in (B) and (D) after normalizing the maximum signal in the image. (G) NH2 channel from (C) after normalizing the maximum signal in the image. (H) OH channel from the difference between normalized images (C) and (D).

Reproduced, with permission, from McMahon et al. [39].