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. 2011 May;25(5):1461–1473. doi: 10.1096/fj.10-170944

Figure 2.

Figure 2.

VEGF-B is dispensable for the sensory nervous system and vasculature. A) Number of surviving primary DRG neurons isolated from WT and VEGF-B−/− mice is not different after 0, 3, and 7 d in culture (n=7 wells from 3 mice/genotype; P=NS). B, C) Whole-mount preparations of the hind-paw dermis from WT (B) and VEGF-B−/− (C) mice stained for the pan-axonal PGP9.5 marker reveal that the density of innervating sensory nerve axons does not differ (n=3–4/group; P=NS). D, E) Staining for the endothelial CD31 marker reveals that there are no differences in the vascular density of the paws of WT (D) and VEGF-B−/− (E) mice in baseline conditions (n=5–6/group; P=NS). Scale bars = 50 μm.