Table 2. Effects of DTG on Concurrent Water Self-Administration.

Water (ml/kg)
	Vehicle	DTG
Baseline	0.36±0.16	0.29±0.08
Day 1	0.38±0.10	0.65±0.30
Day 2	0.23±0.08	0.16±0.08
Day 3	0.38±0.11	0.52±0.22
Day 4	0.33±0.12	1.18±0.54
Day 5	0.28±0.06	0.82±0.44
Day 6	0.05±0.03	0.90±0.26
Day 7	0.12±0.09	0.82±0.40

Effect of repeated subcutaneous pretreatment (twice a day for 7 days) with the σ receptor agonist DTG on water self-administration (concurrent to ethanol) on a fixed-ratio 1 schedule of reinforcement in sP rats during 60-min sessions (n=8/group). Data represent mean±SEM intake (ml) normalized for body weight. No significant effects on water self-administration were observed.