Fig. 6.
siRNA knockdown of ZNF198, SUZ12 and PML enhances HBV replication. A. Immunoblots of SUZ12, ZNF198 and PML using HepAD38 cells transfected with indicated siRNAs grown as follows: tetracycline addition for 24 h after siRNA transfection (−HBV replication), followed by tetracycline removal for 1 day (+HBV replication). B. Quantification of HBV genome equivalents using template DNA from isolated intracellular virions from HepAD38 cells transfected with indicated siRNAs, grown ± tetracycline for 1, 5 and 10 days.
