Table 2. Effect of incident TB on all-cause mortality among 2,882 HIV-infected men followed for a median of 5.4 years. Multicenter AIDS Cohort Study, 1984 – 2005.

	Person-years of follow-up	AIDS-related mortality (1,072 deaths)
		Number of Deaths	Hazard Ratio	95% Confidence Interval
Marginal structural model *
No TB-disease	21,873	1,060	1
TB-disease	41	12	2.4	1.2, 4.7
Unadjusted
No TB-disease	21,873	1,060	1
TB-disease	41	12	6.0	3.1, 11
Baseline adjusted †			3.0	1.6, 5.9
Fully adjusted ‡			1.3	0.6, 2.5

^*White ethnicity, age, calendar year, and CD4 cell count and viral load at study entry were included as regressors. Time-varying CD4 cell count, nadir of CD4 cell count, viral load, peak viral load, PCP, anti-PCP prophylaxis, fever or sweats, MAC, and non-TB ADC were used to compute weights for inverse probability of TB, and censoring (see text)

^†Adjusted for all time-fixed variables listed above

^‡Adjusted for all time fixed and time-varying variables listed above