Table 2.
Variable | Baseline | 6-Month | F | p | d | β |
---|---|---|---|---|---|---|
M (SD) | M (SD) | |||||
Neuropsychological Performance | ||||||
Global Cognitiona | ||||||
3MS | 90.03 (7.14) | 87.83 (8.53) | 4.61 | .04* | 0.28 | .99 |
Memorya | ||||||
HVLT-R Learning Trial | 19.37 (5.74) | 19.01 (5.96) | 0.16 | .70 | 0.05 | .17 |
HVLT-R Delayed Recall | 6.10 (3.23) | 5.17 (3.56) | 3.54 | .07† | 0.27 | .95 |
HVLT-R Recognition | 8.80 (2.93) | 7.80 (3.58) | 2.62 | .12 | 0.31 | .89 |
Attention/Executive Functionb | ||||||
Trail Making Test A (sec) | 50.24 (27.49) | 50.14 (19.39) | <0.01 | .97 | <.01 | .05 |
Trail Making Test B (sec) | 134.48 (67.52) | 156.66 (85.68) | 4.8 | .04* | 0.29 | .99 |
Frontal Assessment Battery | 14.45 (1.97) | 14.48 (1.92) | 0.01 | .92 | 0.02 | .06 |
Letter-Number Sequencing | 7.28 (2.85) | 7.41 (2.67) | 0.22 | .64 | 0.05 | .08 |
Digit Symbol Coding | 46.66 (15.52) | 47.62 (11.79) | 0.08 | .78 | 0.07 | .16 |
Languagea | ||||||
Boston Naming Test | 53.93 (5.46) | 54.73 (5.12) | 1.82 | .19 | 0.15 | .73 |
Animal Naming | 17.67 (6.16) | 16.03 (4.81) | 6.19 | .02* | 0.30 | .99 |
Cardiovascular Fitnessc | ||||||
2-minute Step Test | 75.56 (17.97) | 85.11 (17.58) | 7.86 | .01** | 0.54 | .99 |
Blood Markersd (pg/ml) | ||||||
β-amyloid 1–38 | 80.90 (162.51) | 89.57 (194.23) | 0.06 | .81 | 0.05 | .08 |
β-amyloid 1–40 | 274.52 (111.13) | 302.84 (169.72) | 1.12 | .30 | 0.20 | .58 |
β-amyloid 1–42 | 107.67 (193.45) | 116.75 (204.52) | 0.07 | .80 | 0.05 | .08 |
Note. 3MS = Modified Mini Mental Status Examination; HVLT-R = Hopkins Verbal Learning Test-Revised.
denotes N = 30;
denotes N = 29;
denotes N = 27;
denotes N = 31.
p < .05;
p < .01;
p < .10.