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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Pain. 2011 Feb 1;152(4):912–923. doi: 10.1016/j.pain.2011.01.016

Fig. 1.

Fig. 1

Increased kainate-induced cobalt loading in the dorsal horn after CFA injection. (A) Representative examples of kainate-induced cobalt loading in live spinal cord slices in the absence or presence of the NMDA receptor antagonist APV (500 μM) or AMPAR antagonists CNQX (250 μM) and GYKI 52466 (250 μM). (B) The neuronal marker NeuN overlaps with cobalt-uptake in the superficial dorsal horn. (C) CFA (but not saline) injection increased cobalt uptake in dorsal horn neurons on the ipsilateral, but not contralateral, side. (D) Statistical summary of the number of cobalt-positive dorsal horn neurons in laminae I-II (top graph) and laminae III-VII (bottom graph) 24 h after saline and CFA.