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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Pain. 2011 Feb 1;152(4):912–923. doi: 10.1016/j.pain.2011.01.016

Fig. 3.

Fig. 3

AMPAR-mediated currents and [Ca2+]i transients are similar in tonic and transient neurons of naive rats. (A) Representative traces of a somatic membrane current (bottom trace) and associated [Ca2+]i transients (upper traces) recorded from the soma (black trace) and dendrites (grey trace) in tonic neurons during AMPA bath application (5 μM, 60 s). (B, C) Pre-application of AMPAR antagonists NBQX (30 μM, B) and GYKI 52466 (100 μM, C) abolished AMPA-induced current (lower traces) and associated somatic (upper black traces) and dendritic (upper grey traces) [Ca2+]i transients. (D) Pooled results demonstrate that AMPA-induced current amplitudes (left graph) and [Ca2+]i transients (center and right graphs) recorded from soma and dendrites of different groups of SG neurons are similar. ** p < 0.001, *** p < 0.0001 versus the control; NS, not significant.