Table 3.
Clonea | Mutationb | Ploidyc | Median Chromosome #d |
---|---|---|---|
4a (2 passages) | NS | D | 40 |
4a (19 passages) | NS | D/T | 40/80 |
465RK1 | IN | D/T | 39/75 |
468RK1 | IN | D/T | 40/80 |
483RK2 | IN | ND/NT | 37/72 |
468LK2 | MR | D/T | 40/80 |
465LK1 | MR | D/T | 39/79 |
476RK1 | MR | D/T | 40/80 |
468RK2 | CL | NT | 72 |
464RK3 | CL | A/A | 30/59 |
449RK1 | CL | A | 59 |
449RK3 | CL | A | 54 |
449LK2 | CL | ND/NT | 37/72 |
449LK4 | CL | A | 52 |
476RK2 | CL | A/A | 35/64 |
Each mutant clone is designated by the tag number of the mouse, the kidney it was derived from (right or left) and the clone number (e.g., the third mutant clone picked from a kidney is given the number 3). The non-mutant clone 4a was designated from a different numbering system. This clone was examined at 2 and 19 passages after it was established (see text).
NS, non-selected; IE, intragenic event; MR, mitotic recombination; CL, chromosome loss.
D, diploid; T, tetraploid, A, aneuploid; ND, near diploid; NT, near tetraploid.
Median value for chromosome number in each clone.