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. Author manuscript; available in PMC: 2012 May 10.
Published in final edited form as: Stat Med. 2011 Feb 21;30(10):1090–1104. doi: 10.1002/sim.4187

Table II.

Effects of tamoxifen on various life-threatening and severe events, expressed as relative risks compared to placebo.*

Type of event Relative risk 95% Confidence interval
Life-threatening events
 Invasive breast cancer 0.51 0.39 to 0.66
 Hip fracture 0.55 0.25 to 1.15
 Endometrial cancer
 All women 2.53 1.35 to 4.97
 Women ≥50 years old 4.01 1.70–10.90
 Stroke 1.59 0.93 to 2.77
 Pulmonary embolism 3.01 1.15 to 9.27
Severe events
In situ breast cancer 0.50 0.33 to 0.77
 Deep vein thrombosis 1.60 0.91 to 2.86
*

Data from [39].