Table III.
Health outcomes expected in 10,000 forty year old women in five years, each of whom has a uterus and a projected five-year risk of invasive breast cancer of 2 percent.*
| Without tamoxifen | With tamoxifen | Events prevented by tamoxifen | |
|---|---|---|---|
| Life-threatening events | |||
| Invasive breast cancer | 200 | 103 | 97 |
| Hip fracture | 2 | 1 | 1 |
| Endometrial cancer | 10 | 26 | −16 |
| Stroke | 22 | 35 | −13 |
| Pulmonary embolus | 7 | 22 | −15 |
| Net life-threatening events prevented | 54 | ||
| Severe events | |||
| In situ breast cancer | 106 | 53 | 53 |
| Deep vein thrombosis | 24 | 37 | −13 |
| Net severe events prevented | 38 | ||
*
Data from [38].