. Author manuscript; available in PMC: 2011 Dec 23.

Published in final edited form as: J Med Chem. 2010 Nov 24;53(24):8642–8649. doi: 10.1021/jm1010447

Table 2.

Summary of intestinal Ca transport.

Compound	Structure of a side chain (R)	Compd No.	Dose level (pmol/rat/day)	Intestinal Ca transport (increase in S/M ratio^* compared to Vehicle)
1α,25-(OH)₂D₃	-	1	260	3.2
		4	260	4.0
		5	260	1.5
		6	260	1.4
		7	260	1.6
		8	260	2.8
		9	35100	2.4
		10	7020	3.0
		13	35100	3.0
		14	7020	3.2
		11	35100	1.4
		15	35100	1.6
		16	21060	1.6

S/M Ratio = the amount of calcium found in the serosal compartment divided by the amount of calcium present in the mucosal compartment