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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Hepatology. 2011 Feb 11;53(3):810–820. doi: 10.1002/hep.24127

Table 4.

Sensitivity, specificity, percent agreement, and Cohen’s kappa statistic using NAS cutpoint of 5 for classification of NASH diagnosis

NAS NASH Diagnosis
Definite Borderline/not
≥5 407 66 473
≤4 136 325 461
543 391 934

Sensitivity (95% CI): 0.75 (0.72 – 0.78)

Specificity (95% CI): 0.83 (0.80 – 0.85)

Percent agreement (95% CI): 78.4% (0.76 – 0.81)

Kappa (95% CI): 0.57 (0.76 – 0.81)