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. Author manuscript; available in PMC: 2011 Sep 30.
Published in final edited form as: Nature. 2011 Jan 30;471(7340):597–601. doi: 10.1038/nature09797

Figure 1. Increased nicotine intake in α5 subunit knockout mice.

Figure 1

(a) Data are presented as mean (± SEM) number of nicotine infusions earned across a range of nicotine doses. Two-way ANOVA: Genotype F(1,91)=28.57, p<0.0001; Dose F(6,91)=13.69, p<0.0001; Interaction F(6,75)=2.55, p<0.05; n=10–11 per group. (b) Data from [a] are presented as mean (± SEM) total nicotine intake at each dose. Genotype F(1,91)=67.98, p<0.0001; Dose F(6,91)=39.06, p<0.0001; Interaction F(6,791=14.25, p<0.0001.