Skip to main content
. Author manuscript; available in PMC: 2012 Feb 15.
Published in final edited form as: Cancer Res. 2011 Feb 8;71(4):1497–1505. doi: 10.1158/0008-5472.CAN-10-3223

Figure 3. Pre-fusion clusters of BMDCs contain macrophages.

Figure 3

a, 50μm tissue section and 3-dimensional crypt reconstruction of a confocal Z-stack image illustrating GFP-positive BMDCs (green) surrounding the crypt/stem cell niche. Epithelial cells are marked with E-cadherin (red). b-g, Sequential sections through the Z-stack shown in (a). h-i, Pre-fusion cell clusters contain F4/80-positive macrophages (red) consisting of both donor-derived (yellow) and non-donor-derived cells. Nuclei are stained with Hoechst (h; blue). Dashed white lines indicate epithelial/mesenchymal border. Bars=25μm.