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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Nat Chem Biol. 2011 Jan 16;7(3):154–160. doi: 10.1038/nchembio.512

Fig. 1.

Fig. 1

Structures of polycyclic thiopeptides and their side ring formations. (a) NOS and 5’-fluoro-NOS, and thiostrepton. (b) Processing of L-Trp to afford the indolic acid moiety of NOS and the quinalic acid moiety of thiostrepton, respectively, via completely different routes.