Table 2. Hemodynamic values and core temperature of tethered BKα−/− knockout mice and their wildtype (WT) litter mates following fecal peritonitis (FP).
Time 0 (after 24h on tether) |
6h post-fecal slurry | |||
---|---|---|---|---|
WT (n=6) | BKα−/− (n=5) | WT (n=6) | BKα−/− (n=5) | |
Peak Velocity (m.s−1) | 0.84 ± 0.05 |
0.73 ± 0.03 | 0.84 ± 0.08 |
0.73 ± 0.07 |
Stroke Volume (μl) | 41.3 ± 0.05 |
31.9 ± 0.05 | 43.8 ± 0.03 |
39.4 ± 0.03 |
Stroke Volume.weight−1 (μl.mg−1) | 1.17 ± 0.13 |
1.41 ± 0.05 | 1.24 ± 0.08 |
1.73 ± 0.1 |
Heart Rate (bpm) | 596 ± 19 | 600 ± 22 | 541 ± 18 | 518 ± 60 |
Cardiac Output (ml.min−1) | 24.6 ± 3 | 19.1 ± 0.8 | 25.4 ± 1.8 | 20.4 ± 2.9 |
Cardiac Output.weight−1 (ml.min−1.mg− 1) |
0.7 ± 0.09 | 0.85 ± 0.05 | 0.71 ± 0.05 |
0.9 ± 0.12 |
Core temperature | 37.4 ± 0.5 | 37.4 ± 0.8 | 35.7 ± 0.6 | 35.7 ± 1 |