Table 2.
Distribution of sociodemographic characteristics, APOE genotype and APOE allele frequency by ethnic identity
| Ethnic identity | 'White' N = 1674 |
'Mixed' N = 260 |
'Black' N = 395 |
P value X2 |
|---|---|---|---|---|
| Age (mean/SD) | 75.0 (7.0) | 75.7 (7.7) | 74.7 (6.9) | F = 1.7, P = 0.19 |
| Male sex (n/%) | 579 (34.6%) | 95 (36.5%) | 118 (29.9%) | X2 = 4.0, 2df, P = 0.14 |
| Education level (n/%) | X2 = 25.6, 1 df, P < 0.001 | |||
| None | 37 (2.2%) | 7 (2.7%) | 14 (3.6%) | |
| Some | 344 (20.6%) | 55 (21.2%) | 112 (28.5%) | |
| Primary | 543 (32.5%) | 87 (33.5%) | 148 (37.7%) | |
| Secondary | 429 (25.7%) | 62 (23.8%) | 73 (18.6%) | |
| Tertiary | 317 (19.0%) | 49 (18.8%) | 46 (11.7%) | |
| APOE Genotype (n/%) | X2 = 31.4, 1 df, P < 0.001 | |||
| No E4 allele | 1423 (85.0%) | 222 (85.4%) | 298 (75.4%) | |
| Heterozygous (One e4 allele) | 241 (14.4%) | 32 (12.3%) | 77 (19.5%) | |
| Homozygous (Two e4 alleles) | 10 (0.6%) | 6 (2.3%) | 20 (5.1%) | |
| APOE allele frequency | X2 = 42.6, 4 df, P = < 0.001 | |||
| E2 | 0.058 | 0.063 | 0.072 | |
| E3 | 0.864 | 0.852 | 0.780 | |
| E4 | 0.078 | 0.085 | 0.148 | |