Table 1.

Annualized incidence of IS in Germany

					Definite IS rate per 100,000 child years
Age (a) at diagnosis (year)	Number of definite completed IS cases	Estimated IS cases based on global incidence**	Time at risk years	Population at risk*	Uncorrected incidence based reported cases (definite) via ESPED	Corrected incidence ** [95%-CI]
0 < a < 1 year	358	813	2	673,139	26.6	60.4 [48.3;72.1]
0 < a < 2 years	647	1,402	2	1,361,627	23.8	51.5 [41.7;61.1]
All (< 15 years)	1,200	2,371	2	11,441,367	5.2	10.4 [8.6;12.1]

*Population data for 2006 provided by the German Federal Office for Statistics

**The corrected incidence is estimated by a maximum likelihood approach (taking into account the underreporting)

Uncorrected annual IS incidence α in Germany based on the ESPED data and corrected IS incidence estimated by a maximum likelihood approach which takes into account the underreporting.