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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Nat Immunol. 2011 Mar 20;12(5):434–440. doi: 10.1038/ni.2012

Figure 2.

Figure 2

Immunoglobulin secretion in emptyhive mice. (a) Total immunoglobulins as measured in the serum of 12–24 week-old naive mice. NP-specific antibodies were measured 7, 14 or 28 days after immunization of 12 week-old mice with NP-Ficoll (b) or alum-precipitated NP-CGG (c). Different capture antigens were used to discriminate between total (NP23-BSA) and high-affinity (NP4-BSA) IgG1 in response to NP-CGG. Each symbol represents an individual mouse from one experiment. P values indicated under plots were calculated by unpaired t-tests comparing wild-type and emptyhive groups. ns, not significant (P > 0.05).