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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Nat Immunol. 2011 Mar 20;12(5):434–440. doi: 10.1038/ni.2012

Figure 5.

Figure 5

Partial correction of the emptyhive phenotype by a BCR transgene. The emptyhive mutation was combined with the MM4 transgene (a, b) or the LC2 light chain transgene, VH10tar knockin allele, or both (SWHEL) (c, d). Frequencies of CD19+ cells in blood (a, c), or B cell subsets in bone marrow (b, d) as determined by flow cytometry. An unpaired t-test was performed in (a) with comparison to the emptyhive non-transgenic group. For (c), a one-way ANOVA followed by Bonferroni post test was used, with reference to the emptyhive non-transgenic group. *P < 0.05, ***P < 0.001. Each symbol represents an individual mouse, and data are representative of two independent experiments.