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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Neurobiol Dis. 2011 Feb 3;42(3):292–299. doi: 10.1016/j.nbd.2011.01.019

Figure 6.

Figure 6

The ROS scavenger MnTBAP and the peroxynitrite decomposition catalyst FeTPPS counteract the hippocampal damage produced by activated WT BMM. MnTBAP or FeTPPS (100 μM on 1st day and 50 μM subsequent days until day 4 for both reagents) was added to the culture medium. Cell viability in slices was measured at day 5 by PI uptake. (A): MnTBAP attenuates BMM-induced cell death. *p<0.05 from vehicle (veh), MnTBAP, and non-activated BMM (BMM); #p<0.05 from BMM+LPS/INFγ. (B) FeTPPS attenuates the cell death produced by activated BMM. *p<0.05 from veh, FeTPPS and BMM; #p<0.05 from BMM+LPS/INFγ; for both A and B: analysis of variance and Newman-Keuls test; n=28–35 slices/group from 4–5 separate experiments.