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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: J Comp Neurol. 2011 Jun 1;519(8):1526–1545. doi: 10.1002/cne.22582

Figure 1.

Figure 1

The biological activity of BDNF remaining in the osmotic minipumps after 30 days of implantation in 2 animals was assessed for its ability to promote the survival of cultured SG neurons. BDNF from one minipump was about as effective as 20 ng/ml fresh BDNF (about 20% of the original concentration), and the BDNF from the second minipump was as effective as 30 ng/ml fresh BDNF or approximately 30% of the original concentration (and not significantly different from the fresh BDNF control) after 30 days of implantation. Data generously provided by Dr. Steven Green at the University of Iowa.