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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: J Comp Neurol. 2011 Jun 1;519(8):1526–1545. doi: 10.1002/cne.22582

Figure 4.

Figure 4

a. The numerical density of SG neurons is shown for 10% cochlear sectors from base to apex, with data expressed as percentage of normal for normal adult cats and for a control group of neonatally deafened animals studied at 30 days of age (age when other groups were implanted). SG survival is significantly reduced in the 30 day old deafened group (adult mean, 91 nucleoli [100 μm]3 ; 30-day deaf mean, 70 nucleoli [100 μm]3 ) b. SG numerical density data for neonatally deafened animals studied after 10 weeks of unilateral intracochlear BDNF infusion are shown The BDNF-treated cochleae (black bars) show higher density for all cochlear sectors than the contralateral cochleae (gray bars), although significant neural degeneration is evident on both sides. Averaged over all cochlear sectors, SG cell survival is about 80% of normal after BDNF treatment as compared to about 64% on the other side. c. Data for neonatally deafened animals that received AP infusion show no significant difference between the two sides.