Table 3.
Point estimates (Est), standard error estimates (SE) and 0.95 confidence intervals (CI) for Cτ with breast cancer data
| C-index | New Method | Conventional | ||||
|---|---|---|---|---|---|---|
| τ | Est | SE | CI | Est | SE | CI |
| Without Gene Score Model | ||||||
| 6 | 0.66 | 0.04 | (0.58, 0.74) | 0.68 | 0.04 | (0.60, 0.76) |
| 8 | 0.65 | 0.04 | (0.58, 0.73) | 0.68 | 0.04 | (0.60, 0.75) |
| 10 | 0.65 | 0.04 | (0.57, 0.72) | 0.67 | 0.04 | (0.60, 0.74) |
| 15 | 0.62 | 0.05 | (0.53, 0.71) | 0.67 | 0.04 | (0.60, 0.74) |
| ∞* | NA | NA | NA | 0.67 | 0.04 | (0.60, 0.74) |
| With Gene Score Model | ||||||
| 6 | 0.75 | 0.03 | (0.69, 0.82) | 0.76 | 0.03 | (0.69, 0.82) |
| 8 | 0.75 | 0.03 | (0.68, 0.81) | 0.75 | 0.03 | (0.69, 0.81) |
| 10 | 0.74 | 0.03 | (0.68, 0.80) | 0.75 | 0.03 | (0.69, 0.81) |
| 15 | 0.70 | 0.05 | (0.60, 0.79) | 0.75 | 0.03 | (0.69, 0.81) |
| ∞* | NA | NA | NA | 0.75 | 0.03 | (0.69, 0.81) |
*
Note that no event has been seen after t = 15 in the breast cancer data set. All usable pairs in the dataset are already utilized with τ = 15 for calculation of C-statistics. Thus, the estimates for τ = ∞ and those for τ = 15 are identical. With this data set, the censoring probability at t = 15 was 0.89.