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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Radiat Res. 2010 Nov 17;175(2):150–158. doi: 10.1667/rr2220.1

FIG. 3.

FIG. 3

Overexpression of mitochondria-targeted antioxidant enzymes MnSOD and CAT delivered via adenoviral vectors did not alter the response of B1 cells to low-dose ionizing radiation. Panel A: The plating efficiency of B1 cells transfected with 50 MOI AdBglII is significantly decreased in unirradiated cells compared to cells that were not transduced with adenovirus (*P < 0.001). However, no survival advantage was observed in any irradiated groups of B1 cells transfected with AdMnSOD and/or AdMitoCAT. Columns represent means of three separate experiments. Error bars represent ±1 SEM of 12–18 dishes from three different experiments. Panel B: B1 cells transduced with AdMnSOD and/or AdMitoCAT showed elevated enzyme activity relative to untransduced cells (P < 0.001). Errors represent ±1 SD. Data are averages of three independent experiments.